Top MLB DFS Start‘em/Sit‘em For May 22nd

Boston Red Sox vs. Detroit Tigers top mlb dfs

Another week ends soon, and fantasy players could win cash prizes in today’s top MLB DFS lineups. Thursday’s nine-game slate will end the week with a bang for fantasy players. The weekend is almost here, and Thursday’s top MLB DFS lineups could help players win cash to end the week in style.

Thursday’s games will keep the week going on a hot streak with the Boston Red Sox and the Baltimore Orioles. Another game that fantasy players should have players in tonight’s top MLB DFS lineups should be the Milwaukee Brewers and the Pittsburgh Pirates.

Another week of May is ending, and fantasy players could win cash prizes by using the top MLB DFS lineups for the week.

May 22nd Top MLB DFS Lineup Starters

1B Rhys Hoskins, Milwaukee Brewers at Pittsburgh Pirates ($4,000 – DraftKings/2,900-Fanduel)

To start Thursday night’s top MLB DFS lineups, Rhys Hoskins of the Milwaukee Brewers should be in your lineups. In the loss against the Orioles, Hoskins went 2-5 with a home run during an extra-innings loss.

Hoskins has been hot for the Brewers, and fantasy players could have a great game with him. DFS players could see a home run from the Brewers slugger tonight.

2B Ozzie Albies, Atlanta Braves at Washington Nationals ($4,500 – DraftKings/2,700-Fanduel)

Ozzie Albies of the Atlanta Braves should be in their lineups for Thursday’s top MLB DFS lineups. In a loss against the Nationals on Tuesday, Albies went 1-4 with a run during a brutal loss against the Nationals.

Albies has been a solid player this season for the Braves, and could have another solid game tonight. Fantasy players could see a multi-hit game from the Braves’ veteran infielder.

OF Kerry Carpenter, Cleveland Guardians at Detroit Tigers ($4,000 – DraftKings/3,000-Fanduel)

The last player to have for your fantasy lineups is Kerry Carpenter of the Detroit Tigers in today’s DFS lineups. In the win against the Cardinals, Carpenter went 0-3 with a walk and a strikeout.

Carpenter is playing great baseball this season and could bounce back against the Guardians. Fantasy players could expect a multi-hit game, including a home run against the Guardians.

May 22nd Top MLB DFS Benchwarmers

SS Gunnar Henderson, Baltimore Orioles at Boston Red Sox (4,500 – DraftKings/3,100-Fanduel)

Gunnar Henderson is the first player who should be on your top MLB DFS fantasy benches for this Thursday night. In the extra innings win against the Brewers, Henderson went 2-5 with three runs, a walk, and two strikeouts.

Henderson has been struggling this season and could have another rough game against the Red Sox. Fantasy players could have another multi-strikeout game for Henderson tonight for fantasy lineups.

OF Randy Arozarena, Seattle Mariners at Houston Astros ($4,500 – DraftKings/3,200-Fanduel)

Randy Arozarena of the Seattle Mariners is another player who should be on your fantasy benches tonight for DFS lineups. In a win against the White Sox, Arozarena went 0-4 with a strikeout against the White Sox.

 Arozarena has been struggling this season and could have another poor game against a division rival. Fantasy players could see another hitless game from the Mariners’ slugging veteran outfielder.

3B Jose Ramirez, Cleveland Guardians at Detroit Tigers ($5,800 – DraftKings/3,600-Fanduel)

Jose Ramirez of the Cleveland Guardians should be the last player on your top MLB DFS bench for the night. During a crushing loss against the Twins, Ramirez went 3-5 with a run, an RBI, and a strikeout.

The Guardians have been sluggish this season, and Ramirez could have a bad game against a hot Tigers team tonight. DFS players could see a rare multi-strikeout game from the Guardians’ star veteran against a divisional rival.

Total Apex Media Stack Of The Day

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Apr 29, 2025; Toronto, Ontario, CAN; Boston Red Sox third baseman Alex Bregman (2) rounds second base after hitting a solo home run against the Toronto Blue Jays during the first inning at Rogers Centre. Mandatory Credit: John E. Sokolowski-Imagn Images

Thursday’s top MLB DFS stack should be the Boston Red Sox, Alex Bregman, Rafael Devers, and Jarren Duran. Boston has been playing well, winning three of six games, including a series win against the New York Mets, and could keep its hot streak going.

The Red Sox will play against an Orioles team with a nightmare of a season, and fantasy players could win big in today’s top MLB DFS lineups.

Bregman has been playing well for the Red Sox this season and could have another great game tonight against the Orioles. In the loss against the Mets, Bregman went 0-4 with four strikeouts.

Bregman, while he had a cold game last night, had a solid series with an RBI and two hits against the Mets. Fantasy players could see Bregman have a multi-hit game for the Red Sox and DFS lineups tonight.

Along with Bregman for today’s top MLB DFS lineups is Devers, who is having another solid season for the Red Sox. Devers had a great series against the Mets with an RBI during the three-game series.

Devers has been amazing with the Red Sox in hitting this season, and could have a home run against the Orioles in tonight’s top MLB DFS lineups.

The last player for tonight’s MLB DFS stack of the night is Duran and his hot hitting for the Red Sox. Duran had a solid game, with a 1-3 game with an RBI against the Mets last night.

The Red Sox’s outfielder has been playing his best baseball in May, and could keep his hot hitting against the Orioles. Fantasy players could get a lot of money in today’s top MLB DFS lineups and stacks in today’s pick’em games.

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