This matchup features two young quarterbacks leading their teams through a wide-open AFC playoff race. Both the Colts and Chargers are in striking distance of postseason contention, and this game could have major implications down the stretch. Expect a fast-paced, high-scoring affair with plenty of fantasy fireworks on both sides.
🏈 Quick Start/Sit Table
| Player | Team | Status | Fantasy Note |
| 🐎 Daniel Jones | Colts | ✅ Start | Great matchup vs. defense allowing 20+ pts per game |
| 🐎 Jonathan Taylor | Colts | ✅ Start | Prime spot for a breakout; Chargers can’t stop the run |
| 🐎 Michael Pittman Jr. | Colts | ✅ Start | Target magnet; due for a bounce-back and possible TD |
| 🐎 Tyler Warren | Colts | ✅ Start | Rookie TE on a hot streak; solid red-zone target |
| 🐎 Josh Downs | Colts | 💪 Flex | Reliable WR2 in deep leagues; volume keeps him viable |
| ⚡ Justin Herbert | Chargers | ✅ Start | Strong QB1 option vs. a defense that gives up chunk plays |
| ⚡ Konami Vidal | Chargers | 💪 Flex/Start | Took over the backfield; 120+ yds last week, momentum rolling |
| ⚡ Ladd McConkey | Chargers | 💪 Flex | Back-to-back TD games; trending upward in usage |
| ⚡ Quentin Johnston | Chargers | ❌ Sit | Battling injury and inconsistent; keep benched for now |
✅ STARTS
Daniel Jones – QB, Colts
Jones draws a favorable matchup against a Chargers defense that has been generous through the air, allowing over 20 fantasy points per game to opposing quarterbacks. With time to throw and his mobility as a bonus, Jones is a safe start with upside for multiple scores.
Jonathan Taylor – RB, Colts
The matchup screams “breakout game.” The Chargers’ front has struggled to contain running backs in recent weeks, and Taylor’s combination of burst and vision should lead to a big day. Expect 100+ total yards and a touchdown.
Michael Pittman Jr. – WR, Colts
Pittman may have had a quieter week recently, but his target share remains elite. As Jones’ top option, Pittman is always a threat in the red zone. Expect him to rebound in a matchup that favors big outside receivers.
Tyler Warren – TE, Colts
The rookie tight end continues to produce in key moments, finding the end zone again last week. With defenses starting to key on Pittman, Warren should find plenty of room to operate in the seams. A strong TE1 streamer this week.
💪 FLEX PLAYS
Josh Downs – WR, Colts
Downs continues to be a reliable short-yardage and possession option. His chemistry with Jones makes him a safe flex play in deeper formats, especially in PPR leagues.
Kimani Vidal – RB, Chargers
Vidal exploded for over 120 yards last week and looked like the clear lead back in this offense. The Colts have been middle-of-the-pack against the run, giving Vidal a strong shot at another productive outing.
Ladd McConkey – WR, Chargers
McConkey has come to life over the past two weeks, scoring in back-to-back games. His speed and versatility give Herbert a reliable second option behind the top wideout. He’s a sneaky flex play with touchdown upside.
✅ START
Justin Herbert – QB, Chargers
Herbert continues to look sharp and efficient, spreading the ball around with confidence. The Colts defense has given up points to nearly every QB they’ve faced, making Herbert a locked-in QB1 this week. Expect 275+ yards and multiple scores.
❌ SIT
Quentin Johnston – WR, Chargers
Johnston’s inconsistency and injury status make him too risky to trust this week. Until he returns healthy and reclaims a steady target share, keep him on the bench.
🔮 Fantasy Outlook Summary

This one could easily turn into a shootout. Daniel Jones and Justin Herbert are both trending upward, while Jonathan Taylor and Kimani Vidal headline a matchup full of big-play potential. Look for Pittman and McConkey to make key contributions through the air, and keep an eye on Tyler Warren, who’s emerging as one of fantasy’s most reliable rookie tight ends.
