Kansas City Chiefs at Tennessee Titans Preview, Prediction & Odds | Week 16, 2025

kansas city chiefs chargers
Kansas City Chiefs (6-8) at Tennessee Titans (2-12)
Game Details: Sunday, December 21, 1:00 p.m. EST
Location: Nissan Stadium, Nashville, TN
Where to Watch: CBS

Week 16 Matchup

With both teams eliminated from playoff contention, the Kansas City Chiefs and Tennessee Titans battle for pride and for betting props. After getting eliminated, the Chiefs on Sunday look to win for their pride and potential last rides for Andy Reid and Travis Kelce, while the Titans are looking to a brighter season next year, even after a disastrous season at home.

Betting Odds

Team Spread Money Line Total
Kansas City
Chiefs
-2.5-154Over 37.5
Tennessee Titans +2.5+130Under 37.5

** Odds Subject to Change – Courtesy of FanDuel**

Tale of The Tape

Kansas City
Chiefs
Team Stats – Avg Per GameTennessee Titans
23.4Points Per Game16.1
244.0Passing Yards Per Game161.9
113.9Rushing Yards Per Game88.6
19.1Opponents Points Per Game Allowed28.1
204.0Opponents Pass Yards Allowed 233.0
99.1Opponents Rush Yards Allowed 123.6

Statistics from various online sources, courtesy of ESPN and FOX Sports

Key Details

tony pollard titans
Aug 9, 2025; Tampa, Florida, USA; Tennessee Titans running back Tony Pollard (20) runs the ball in for a touchdown against the Tampa Bay Buccaneers during the first half at Raymond James Stadium. Mandatory Credit: Kim Klement Neitzel-Imagn Images

Kansas City Chiefs

From the cusp of winning another Super Bowl to not making the playoffs is a tale as old as time for the Kansas City Chiefs and their dynasty ending. Kansas City has been having a poor season with their offense struggling with poor game planning and poor play from their receivers and run game. The Chiefs’ run game has been non-existent with Kareem Hunt and Isaiah Pacheco having poor seasons.

Now, without Mahomes for the rest of the season, the Chiefs’ offense could face more regressions. Kansas City’s defense has been playing well by allowing less than 19 points per game, but they need to rely on their offense, and it has been a nightmare, especially in their loss against the Chargers, to knock them out of the playoffs.

Tennessee Titans

While the Kansas City Chiefs are a dysfunctional team this season, they are facing a literally dysfunctional organization in the Tennessee Titans. The Titans this season have been a disaster with firing their head coach in the middle of the season, owners meddling in their affairs, and potentially ruining their top prospect in Cam Ward in a disaster of a rookie campaign. 

Tennessee’s offense is ranked in the bottom pack of the NFL due to its ineffectiveness in running and throwing the ball. The Titans’ defense, while a solid unit in name only, has been awful, allowing nearly 30 points a game. This Titans team has been a disaster, and bettors should not touch them, even with their last loss, due to their ineffectiveness in anything good.

Prediction

It’s an easy choice for bettors for this game, and while the Kansas City Chiefs have been inconsistent, they are not the Tennessee Titans. Kansas City has an elite defense that could shut down the Titans’ offense, especially with a rookie quarterback at the helm. While the Titans could fight back, the Chiefs could easily win and cover due to how the Titans are a poorly run organization.

Final Pick

Kansas City Chiefs  -2.5

Under 37.5

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