Indianapolis Colts vs. Tennessee Titans Week 8 Start Em Sit Em Fantasy Football Preview

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The Colts are set for a stat-padding special this week as they face a reeling Titans team that’s struggled to contain explosive offenses. Indianapolis has found its groove behind Daniel Jones and Jonathan Taylor, and fantasy managers everywhere are ready for another big scoring day. Expect the Colts to roll early and keep the momentum going as one of the AFC’s most fantasy-friendly units.

🔥 Start ’Em / Sit ’Em Quick Table

PlayerTeamFantasy StatusOutlook
Daniel JonesColts✅ StartHot hand; could toss 3 TDs vs soft Titans secondary
Jonathan TaylorColts✅ StartLocked-in RB1, fresh off 4 TDs
Tyler WarrenColts✅ StartRookie TE thriving with Jones, high yardage upside
Michael Pittman Jr.Colts✅ StartChemistry with Jones keeps growing; WR1 play
Alec PierceColts💪 SleeperMore yards than Pittman — touchdown due this week
Titans D/STTitans❌ SitAvoid at all costs vs red-hot Colts offense

🔥 Start ’Em

Daniel Jones (QB, Colts)

Jones is proving that the Colts’ gamble on him is paying off. After tossing two touchdowns last week, he’s in a prime position to add a third against a Titans defense that’s giving up big plays downfield. With a strong supporting cast and clean pocket protection, Jones is a top streaming QB for Week 8.

Jonathan Taylor (RB, Colts)

Four touchdowns. That’s all you need to know. Taylor is absolutely rolling, and there’s no reason to believe he’ll slow down this week. The Titans’ front has been soft up the middle, and Taylor should have his way — expect another two-touchdown day and over 100 total yards.

Tyler Warren (TE, Colts)

The rookie tight end continues to impress. He’s becoming a key piece of the passing attack and a reliable red-zone option for Jones. Warren’s athleticism and route running make him a tough cover for Tennessee’s linebackers. Pencil him in for 80 yards and a score — he’s an every-week starter moving forward.

Week 8 NFL Sunday Fantasy Football Blitz: Tyler Warren Will Pile up Points for the Colts – John Laghezza via Fantasylife.com

Michael Pittman Jr. (WR, Colts)

Pittman has been revitalized since Jones took over, racking up five touchdowns on the season. His combination of size and chemistry with his QB makes him a nightmare for smaller corners. He’s an automatic WR1/2 start this week with touchdown potential yet again.

💪 Sleeper: Alec Pierce (WR, Colts)

Pierce has quietly outgained Pittman in yardage this season, but the touchdowns haven’t followed — yet. This feels like the week that changes. With defenses focusing on Pittman and Taylor, Pierce should see one-on-one looks and at least one deep-shot opportunity. He’s a perfect DFS sleeper or WR3 flyer.

Alec Pierce and More Emergency Fantasy Football Starts for Week 8 Bye-Mageddon – Fantasylife.com

🚫 Sit ’Em

Sep 21, 2025; Nashville, Tennessee, USA; Tennessee Titans wide receiver Elic Ayomanor (5) celebrates his touchdown with wide receiver Calvin Ridley (0) against the Indianapolis Colts during the second half at Nissan Stadium. Mandatory Credit: Steve Roberts-Imagn Images

Titans Defense

No defense wants to face this version of the Colts. Between Jones’ efficiency, Taylor’s dominance, and the emergence of Warren, Tennessee is simply outmatched. Expect a high-scoring affair where the Titans D/ST offers no fantasy value — bench them confidently.

⚙️ Fantasy Outlook

This one could get out of hand early. The Colts are firing on all cylinders and have become one of the most reliable fantasy offenses week to week. Daniel Jones and Jonathan Taylor should headline the scoring again, while Pittman and Warren continue to shine. For those looking for a sneaky play, Alec Pierce could finally hit pay dirt.

Final Verdict:

Start: Jones, Taylor, Pittman, Warren

Sleeper: Pierce

Sit: Titans Defense

This matchup is tailor-made for fantasy fireworks — and once again, the Colts are ready to deliver.

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