The 49ers completely out-schemed the Eagles last week and produced massive fantasy numbers across the board. This week presents a tougher challenge against a divisional opponent, but the offensive firepower on both sides still points toward a high-scoring affair. Expect a 27–30 type game, making this slate rich with DFS opportunities. This game should be a thriller.
Divisional familiarity often condenses usage to trusted players, which is exactly what DFS players want in a single-game format.
DFS Starts
Brock Purdy — QB, 49ers
DK: $11,600 | FD: $16,500
Purdy is playing lights-out football, and the extra week of preparation should help the 49ers stay hot. Seattle’s defense is also coming off a bye, but Purdy’s efficiency and comfort in this offense keep his floor high. He spreads the ball well and benefits from elite yards-after-catch weapons.
DFS role:
• Strong cash-game Captain candidate
• Safe flex in all builds
• Correlates with multiple pass catchers
Christian McCaffrey — RB, 49ers
DK: $13,800 | FD: $18,500
McCaffrey is in full assault mode. He’s the centerpiece of the offense and touches the ball in every situation: early downs, passing game, and red zone. Expect heavy volume and at least one score, with multi-touchdown upside always in play.
DFS role:
• Highest raw-points player on the slate
• Elite Captain/MVP in all formats
• Matchup- and script-proof
Sam Darnold — QB, Seahawks
DK: $9,800 | FD: $14,000
Darnold should shake off the rust early and get into a rhythm. Seattle will likely need to throw to keep pace, and Darnold has enough weapons to move the ball, especially with Jaxon Smith-Njigba, AJ Barner, and Zach Charbonnet involved in the passing game.
DFS role:
• Volume-based flex
• Works best in Seahawks comeback scripts
• Viable GPP quarterback pivot
Jaxon Smith-Njigba — WR, Seahawks
DK: $8,600 | FD: $12,500
JSN will likely see plenty of Deommodore Lenoir again, but it’s playoff time, and Seattle will need him heavily involved. His route-running and yards-after-catch ability give him both floor and ceiling in a pass-heavy game script.
DFS role:
• Core flex option
• Strong pairing with Darnold
• Viable tournament Captain
Zach Charbonnet — RB, Seahawks
DK: $8,400 | FD: $12,000
Charbonnet’s value continues to rise, especially if his passing-game usage holds. His ability to contribute as both a runner and receiver gives him DFS stability, particularly if Seattle trails and leans into checkdowns.
DFS role:
• High-floor flex
• Positive leverage over Kenneth Walker
• Excellent PPR-style Showdown play
Flex & Value Plays
Jauan Jennings — WR, 49ers
DK: $6,800 | FD: $10,000
Jennings will need to have a bigger impact in the passing game to pay off, but divisional matchups often push secondary receivers into meaningful roles. If Seattle focuses on McCaffrey and the top options, Jennings can quietly deliver.
DFS role:
• Salary-saving flex
• Works best in Purdy stacks
• Moderate ceiling
Demarcus Robinson — WR, 49ers
DK: $6,400 | FD: $9,500
Robinson stepped up in a big way with the absence of George Kittle and Ricky Pearsall. Expect five to six targets or more, particularly if Seattle sells out to stop the run and the middle of the field.
DFS role:
• Strong value flex
• Under-owned tournament play
• Red-zone upside
Sleeper: Kyle Juszczyk — FB, 49ers
DK: $4,200 | FD: $7,000
Juszczyk may again be called upon to help in the passing game. He’s a true Swiss Army knife, and with attention focused on McCaffrey and the receivers, he can sneak into the red zone for a score.
DFS role:
• Low-cost salary relief
• High-leverage GPP dart
• Touchdown-dependent upside
AJ Barner — TE, Seahawks
DK: $5,200 | FD: $8,500
Barner continues to represent well as a red-zone threat. He often gets lost in coverage and is one of Seattle’s better end-zone options in condensed-field situations.
DFS role:
• TD-dependent flex
• Strong tournament leverage
• Correlates with Darnold
DFS Sits
Kenneth Walker — RB, Seahawks
DK: $9,200 | FD: $13,000
Walker’s DFS value currently relies almost entirely on breaking long runs. Against a disciplined 49ers defense in a playoff environment, those chances are limited. With Charbonnet handling more passing work, Walker is a risky DFS investment this week.
DFS Construction: Cash vs. GPP
CASH GAME CONSTRUCTION
Priority: Floor, Volume, Raw Points
Captain/MVP: Christian McCaffrey or Brock Purdy
Cash Core:
• McCaffrey (Captain)
• Brock Purdy
• Sam Darnold
• Jaxon Smith-Njigba
• Zach Charbonnet
Why it works:
• Locks in the highest-usage players
• Minimizes touchdown variance
• Covers both game scripts
Cash mindset: Don’t fade volume. Let the stars carry you.
GPP CONSTRUCTION
Priority: Ceiling, Correlation, Ownership Leverage
Top GPP Captains:
• Jaxon Smith-Njigba
• Zach Charbonnet
• Brock Purdy (without McCaffrey, Captain)
Seahawks-Lean GPP Build
• Captain: JSN
• Flex: Darnold
• Flex: Charbonnet
• Flex: Purdy
• Value 49er
Script: Seattle pushes pace and forces volume.
Why the 49ers’ Kyle Juszczyk may be the key to replacing George Kittle – Jason Apopa Niners Natin
49ers Skill-Player GPP Build
• Captain: McCaffrey or Purdy
• Flex: Jennings or Robinson
• Flex: Juszczyk
• Bring-back: JSN or Barner
Script: San Francisco scores through multiple secondary options.
GPP mindset: Build for the outcome that blocks the most popular builds.
Final Take
This divisional showdown has shootout potential, even with familiarity on both sides. San Francisco’s offense remains elite, but Seattle has enough firepower to force volume and elevate DFS ceilings. Cash games should anchor around McCaffrey and Purdy, while GPPs are won by correctly identifying which secondary options step up when defensive attention shifts.
