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The Lions looks to knock off another AFC Giant in the Chiefs Sunday Night.

The Packers are refreshed off the bye and look for an early start against Flacco and the Bengals.

This is Game of the Week, as it is the NFC Showdown Between Two 4–1 Powerhouses in the 49ers and Buccaneers.

Two 1–4 teams enter this matchup desperate for a win, and perhaps more importantly, to prove they belong in the conversation beyond 2025.

The Pittsburgh Steelers come into this AFC North clash looking confident and composed, led by rookie quarterback Dillon Gabriel, who impressed in his first career start last week.

Panthers RB Dowdle calls out Dallas Defense for their matchup in Week 6.

The Colts head into this matchup sitting at 4-1 and firmly in control of the AFC South.