Both teams come into this one with playoff aspirations and momentum on their side. The 49ers are finally getting healthy with the returns of George Kittle and Jauan Jennings, while the Falcons continue to ride the strong play of rookie QB Michael Penix Jr. and star RB Bijan Robinson. With both squads desperate for a statement win in the tight NFC race, this matchup has plenty of fantasy fireworks potential.
🔥 Quick Start Table
| Player | Team | Designation | Notes |
| 🔥 Mac Jones (QB) | 49ers | Start | Filling in for Purdy, has a chance to impress in a favorable spot |
| 🔥 Christian McCaffrey (RB) | 49ers | Start | Weekly must-start; volume and scoring upside |
| 💪 George Kittle (TE) | 49ers | Flex/Start | Returns to add another dimension to the offense |
| 💪 Kendrick Bourne (WR) | 49ers | Flex | Risky play with other targets returning |
| 💪 Jauan Jennings (WR) | 49ers | Flex | Deep-league option; watch his snap count |
| 🧊 Jake Tonges (TE) | 49ers | Sit | Kittle and Jennings’ return kills his value |
| 🔥 Michael Penix Jr. (QB) | Falcons | Start | Coming off strong game vs. Buffalo; solid streaming option |
| 🔥 Bijan Robinson (RB) | Falcons | Start | Top fantasy back, elite floor and ceiling |
| 🔥 Drake London (WR) | Falcons | Start | Falcons’ clear WR1 and red-zone focal point |
| 🧊 Kyle Pitts (TE) | Falcons | Sit | Inconsistent usage and minimal impact |
| 🧊 Tyler Allgeier (RB) | Falcons | Sit | Not enough touches or passing involvement |
🔥 Starts
Mac Jones, QB, 49ers
With Brock Purdy due back next week, this could be Jones’s last chance to show what he’s got, and it comes in a great matchup. The Falcons’ defense has been inconsistent against the pass, and Jones should capitalize with the 49ers’ full arsenal of weapons at his disposal. Expect a multi-touchdown day.
Christian McCaffrey, RB, 49ers
CMC continues his weekly rampage through defenses. Expect another game filled with explosive runs, receptions out of the backfield, and at least one touchdown. He’s the most reliable player in fantasy football, period.
Michael Penix Jr., QB, Falcons
Penix continues to impress, throwing for 250 yards and a score against a tough Buffalo defense last week. The 49ers are strong up front, but Penix’s poise and ability to spread the ball make him a viable start in deeper leagues or as a streaming option.
Bijan Robinson, RB, Falcons
Robinson has been nothing short of elite. He’s the engine of Atlanta’s offense and is a threat to score both on the ground and through the air. Pencil him in as a locked-and-loaded RB1 again this week.
Drake London, WR, Falcons
London has been unstoppable this year, commanding heavy targets and producing like a WR1. Even against the Niners’ tough secondary, his volume and chemistry with Penix make him an automatic start.
💪 Flex Plays

George Kittle, TE, 49ers
Kittle’s return gives this offense another spark. He’s always a big-play threat and a top red-zone target when healthy. Even if the volume isn’t massive, his touchdown upside is undeniable.
Kendrick Bourne, WR, 49ers
A bit of a risky play with Kittle and Jennings back, but Bourne still has flex value in what could be a high-scoring game. If you’re dealing with injuries or byes, he’s worth a look.
Jauan Jennings, WR, 49ers
Jennings makes his return and should see a handful of targets as the offense opens up. Consider him a deep-league flex option with moderate upside depending on how the 49ers’ snap distribution shakes out.
🧊 Sits
Jake Tonges, TE, 49ers
With Kittle and Jennings back, Tonges becomes the odd man out in this passing attack. He can safely remain on waivers.
Kyle Pitts, TE, Falcons
Pitts has struggled to carve out any consistent role, and until his target share improves, he can’t be trusted in starting lineups.
Tyler Allgeier, RB, Falcons
Allgeier’s touches have evaporated with Robinson dominating the workload. Without passing game usage, he’s an easy sit this week.
Bottom Line:
Both teams are fighting for playoff positioning and have plenty of fantasy relevance. Start your studs: McCaffrey, Robinson, and London are set for big days. Kittle’s return boosts the 49ers’ offense, while Penix keeps Atlanta competitive. Expect a hard-fought, high-scoring affair in what could be a playoff preview down the line.
Prediction: 49ers 27, Falcons 24
